BIOGRAPHICAL SKETCH

Academic & Professional Background

• B.Sc. (Chemistry, Botany & Zoology) 1970 - J.V. College, Baraut UP, India
• M.D. (Medicine, Surgery) 1974 - Lady Hardinge Medical College, New Delhi, India
• Rotating Internship 1975 - Lady Hardinge Hospital
• Residency 1980 - Schwab Rehabilitation Hospital, Chicago, Illinois
• Residency 1983 - Hines VA Hospital/Loyola University Medical Center, Maywood, Illinois

Current Research Interests

• Clinical Trials in Stroke Prevention

Selected Publications

ACE Investigators. Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: A randomized controlled trial. Lancet 353:2179-2184, 1999.

Kang SS, Littooy FN, Gupta SR, et al. Higher prevalence of abdominal aortic aneurysms in patients with carotid stenosis but without diabetes. Surgery 126:687-692, 1999.

Yilmaz EY, Gupta SR, Mlcoch AG, Moritz T. Aspiration following stroke. J Neuro Rehab 12:61-64, 1998

Barnett HJM, Taylor W, Eliasziw M, Fox AJ, Fergussion GG, Haynes RB, Rankin RN, Glagett GP, Hachinski VC, Sackett D, Thrope KE, Meldrum HE, Gupta S, North American Symptomatic Carotid Endarterectomy Trial Collaborators. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. NEJM 339:1415-1425, 1998.

Gupta SR, Brigell M, Gujrati M, Lee J. Supranuclear eye movement dysfunction in mitochondrial myopathy with tRNALEU mutation. J Neuro Ophth 15:20-25, 1995.

Mlcoch AG, Gupta SR. Pharmacological approaches to the treatment of aphasia. Topics in Stroke Rehab 2:42-48, 1995.

Angelopoulos M, Gupta SR, Kia BA. Primary intraventricular hemorrhage in adults. Clinical Features, Etiology and Outcome. Surg Neuro 44, 1995.

Gupta SR, Mlcoch AG, Scolaro C, Moritz T. Bromocriptine treatment in nonfluent aphasia. Neurology 45:2170-2173, 1995.

Ezekowitz MD, James KE, Nazarian SM, Davenport J, Broderick JP, Gupta SR, Thadani V, Meyer ML, Bridgers SL. Silent cerebral infarction in patients with nonrheumatic atrial fibrillation. Circulation 92:2178-2182, 1995.

Mlcoch AG, Bushnell DL, Gupta SR, Milo TJ. Speech fluency in aphasia: rCBF correlates of recovery using SPECT/IMP neuroimaging. J Neuroimaging 4:6-10, 1994.

Gupta SR, Bastian RB. Use of laryngeal electromyography in predicting recovery after vocal cord paralysis. Muscle Nerve 16:977-978, 1993.

Gupta SR, Mlcoch AG. Bromocriptine treatment in nonfluent aphasia. Arch Phys Med Rehabil 73:373-376, 1992.

Ezekowitz MD, Bridgers S, James KE, Carliner NH, Colhing C, Gornick CC, Hanahan E, Kraus-Steinrauf H, Kurtzke JF, Nazarian SM, Radford MJ, Rickles FR, Shabetai R, Deykin D, Gupta S, et al. Stroke prevention in nonrheumatic atrial fibrillation (SPINAF): The Department of Veterans Affairs Study. NEJM 227:1406-1412, 1992.

Gupta SR. Single photon emission computerize tomography and its application in central nervous system diseases. In: Advances in Clinical Neurosciences. Sinha KK, Chandra P. (Eds.), Ranchi, Bihar, India, Vol. 2, pp 1-9, 1992.

Bushnell DL, Gupta SR, Barnes E, Littooy F, Niemiro M. Evaluation of cerebral perfusion reserve using 5-1 CO2 and SPECT neuroperfusion imaging. J Clin Nuclear Medicine 16:263-267, 1991.

Endean ED, Steffen G, Chmura C, Gupta SR, Littooy FN. Outcome of asymptomatic cervical bruit in a VA population. J Cardiovasc Surg 32:620-626, 1991.

Gupta SR, Bushnell DL, Mlcoch A, Eastman G, Barnes E, Fisher SG. Utility of late N-isopropyl-P(I-123)-iodo amphetamine brain distribution in predicting recovery/outcome following cerebral infarction. Stroke 22:1512-1518, 1991.

Mayberg MR, Wilson, SE, Yatsu F, Weiss DG, Messina L, Hersheu LA, Colhing C, Eskridge J, Deykin D, Winn R, Gupta S, et al. Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis. JAMA 266:3289-3294, 1991.

Gupta SR, Zdonczyk D, Rubino FA. Cranial neuropathy in systemic malignancy in a VA population. Neurology 40:997-999, 1990.

Bushnell DL, Gupta SR, Mlcoch AG, Barnes E. Prediction of language and neurologic recovery after cerebral infarction using SPECT IMP imaging. Arch Neurol 46:665-670, 1989.

Echiverri HC, Rubino FA, Gupta SR, Gujrati. Fusiform aneurysm of the vertebrobasilar system. Stroke 20:1741-1747, 1989.

Gupta SR, Naheedy MH, Young JC, Ghobrial M, Rubino FA, Hindo W. Periventricular white matter changes and dementia. Arch Neurol 45:637-641, 1988.

Merchut MJ, Gupta SR, Naheedy MH. The relationship of retinal artery occlusion and carotid artery stenosis. Stroke 19:1239-1242, 1988.

Gupta SR, Naheedy MH, Elias D, Rubino FA. Post infarction seizures - A clinical study. Stroke 19:1477-1481, 1988.

Projects Completed or Active (Selected)

• African American Antiplatelet Stroke Prevention Study
• Aspirin in Carotid Endarterectomy
• Bromocriptine Treatment in Chronic Nonfluent Aphasia
• North American Symptomatic Carotid Endarterectomy Trial

Research Funding Sources

• National Institutes of Health
• VA Merit Review

Research Methods Employed

• Clinical Research
• Drug Trials