BIOGRAPHICAL SKETCH

Academic & Professional Background

• B.S. (Biology) 1968 - Loyola University, Chicago, Illinois
• Ph.D. (Microbiology) 1974 - Loyola University, Chicago, Illinois
• M.D. (Medicine) 1975 - Northwestern University, Chicago, Illinois
• Internship (Internal Medicine) 1976 - Northwestern University Medical Center, Chicago, Illinois
• Residency (Internal Medicine) 1979 - Medical College of Wisconsin, Milwaukee
• Fellowship (Infectious Disease) 1981 - Medical College of Wisconsin, Milwaukee

Current Research Interests

• Clinical Trials

Selected Publications

Lentino JR. Prosthetic joint infections: Bane of the orthopedists; boon for the infectious diseases specialist. Clinical Infectious Diseases (in press), 2003.

Wright K, Popli S, Gandhi VC, Lentino JR, Reyes CV, Leehey DJ. Paecilomyces peritonitis: Case report and review of the literature. Clinical Nephrology (in press), 2003.

Lentino JR, Rubins J, Searle A. Guidelines for managing community-acquired pneumonia. Federal Practioner 19(Supplement):16-23, 2002.

Lentino JR, Rubins J. Etiology and diagnosis of community acquired pneumonia. Federal Practioner 19(Supplement 7):4-10, 2002.

Lentino JR, Pachucki CT, Rammamurthy S, Turner J. Intramaxillary artery - infusion of amphotericin B for refractory sphenold sinus apergillos. Infections in Medicine 19:335-337, 2002.

Lentino JR, Krasnicka B. Association between initial emperic therapy and decreased length of stay among veteran patients hospitalized with community acquired pneumonia. International Journal of Antimicrobial Agents 19:61-66, 2002.

Lentino JR. Nosocomial pneumonia: More than just ventilator-associated. Current Infectious Disease Reports. 3:266-273, 2001.

Boorgu R, Dubrow AJ, Levin NW, My H, Canaud BJ, Lentino JR, Wentworth DW, Hatch DA, Megerman J, Prosl FR, Gandhi VC, Ing TS. Adjuctive antibiotic/anticoagulant lock therapy in the treatment of bacteremia associated with the use of a subcutaneously implanted hemodialysis access device. ASAIO Journal 46:767-770, 2000.

Lentino JR, Pachucki CT, Byrne R, Lau MT, Bayer D. A cost effective home based parenteral antibiotic infusion program for veteran patients. Federal Practitioner 17:10-15, 2000.

Lentino JR, Baddour LM, Wray M, Wong ES, Yu VL. Staphylococcus aureus and other bacteremias in hemodialysis patients: Antibiotic therapy and surgical removal of access site. Infection 28:355-360, 2000.

Cheng YL, Shek CC, Tsang DNC, Li CS, Lentino JR. Daugirdas JT, Kjellstrand CM, Ing TS. Stability of urea and creatinine in spent hemodialysate. International J of Artificial Organs 23:670-674, 2000.

Lentino JR. Bacterial diseases caused by gram-positive bacilli - Anthrax. In: The Merck Manual, 17th Edition. Berkow R (Ed), Merck Research Laboratories, pp. 1157-1158, 1999.

Lentino JR. Anaerobic bacterial infections. In: The Merck Manual, 17th Edition. Berkow R (Ed), Merck Research Laboratories, pp. 1176-1181, 1999.

Lentino JR, Byrne R. A survey of the usage of aminoglycoside antibiotics in the VA. Federal Practitioner 15:26-31, 1998.

Lentino JR. Anaerobic bacterial infections. In: The Merck Manual of Medical Information - Home Edition, 1st Edition. Berkow R (Ed), Merck Research Laboratories, 1998.

Gutierrez RA, Dawson GJ, Knigge MF, Melvin SL, Heynen CA, Kyrk CR, Young C, Carrick RJ, Schlauder GG, Surrowy TK, Dille BJ, Coleman PF, Thiele DL, Lentino JR, Pachucki C, Mushahwar IK. Seroprevalence of GB Virus C and persistence of RNA and antibody. J Med Virol 53:167-173, 1997.

Lentino JR, Leehey DJ. Infections. In: Handbook of Dialysis, 3rd Edition. Daugirdas JT, Ing TS (Eds), Little Brown and Company, Boston, 1997.

Dawson GJ, Schlauder GS, Pilot-Matias TJ, Thiele D, Leary TP, Murphy P, Rosenblatt JE, Simons JN, Martinson FEA, Gutierrez RA, Lentino JR, Pachucki C, Muerhoff AS, Widell A, Tegtmeier G, Desai S, Mushahwar IK. Prevalence studies of GB Virus-C infection using reverse-transcription-polymerase chain reaction. J Med Virol 50:97-103, 1996.

Lentino JR, Brooks D. Pneumocystis caninii pneumonia and tuberculosis in a Human Immunodeficiency Virus seronegative patient without evidence of the idiopathic CD4+t-lymphopenia syndrome. Clin Infect Dis 18:470-471, 1994.

Lentino JR, Leehey DJ. Infections. In: Handbook of Dialysis, 2nd Edition. Daugirdas JT, Ing TS (Eds) Little Brown and Company, Boston, pp. 469-490, 1994

Patel J, Pachucki CT, Lentino JR. Synergy of L-offoxacin and oxacillin against quinolone resistant methicillin resistant Staphylococcus aureus by the time-kill method. Antimicrob Agents Chemother 37:339-341, 1993.

Leehey DJ, Braun BI, Tholl DA, Chung LS, Gross CA, Roback JA, Lentino JR. Can pharmacokinetic dosing decrease nephrotoxicity associated with aminoglycoside therapy? J Am Soc Nephrol 4:81-90, 1993.

Ward TT, Thomas RG, Fye LL, Arbeit R, Coltman A, Jr, Craig W, Dana BW, Finegold S, Lentino J, et al. Trimethoprim sulfamethoxazole prophylaxis in granulocytopenic patients with acute leukemia. A randomized, double-blind, placebo-controlled VA Cooperative Study. Clin Infect Dis 17:323-332, 1993.

Huston MJ, Lentino JR. Intravenous fleroxacin vs ceftazidime for lower respiratory tract and skin and soft tissue infection. Clin Ther 14:595-602, 1992.

Dorus W, Schaefer M, Pachucki CT, Schaaff DM, Lentino JR. HIV infection in drug abusers: Research implications of descriptive studies. NIDA Res Monogr 109:101-113, 1991.

Lentino JR, Augustinsky J, Weber TM, Pachucki CT. Therapy of serious skin and soft tissue infections with ofloxacin administered by intravenous and oral route. Chemotherapy 37:70-76, 1991.

Lentino JR, Pachucki CT, Holzer TJ, Heynen C, Schaaff D, Schaefer MR, Dorus W. Comparison of radioimmunoprecipitation assay (RIPA) vs Western blot in the confirmation of enzyme linked immunosorbent assay repeatedly reactive sera for HTLV-I. J Infect Dis 163:1387-1388, 1991.

Lentino J, Pachucki C, Schaaff D, Schaefer M, Holzer T, Heynen C, Dawson G, Dorus W. Seroprevalence of HTLV-I/II and HIV-1 infection among male intravenous drug abusers in Chicago. J Acquir Immune Defic Syndr 4:901-909, 1991.

Pachucki CT, Lentino JR, Schaaff D, Schaefer M, Heynen CA, Holzer TJ, Dawson GJ, Dorus W. Low prevalence of sexual transmission of hepatitis C virus in sex partners of seropositive intravenous drug users. J Infect Dis 164:820-821, 1991.

Lentino JR, Preheim LC, Mellencamp MA, Dworzack DL. Oral ciprofloxacin vs parenteral ceftriaxone in the therapy of acute and chronic osteomyelitis. Eur J Clin Microbiol Infect Dis (Special Issue) p. 410-411, 1991.

Lentino JR, Leehey DJ. Infections. In: Handbook of Dialysis, 1st Edition. Daugirdas JT, Ing TS (Eds), Little Brown and Company, Boston, pp. 353-371, 1987

Projects Completed or Active (Selected)

• Antibiotic Treatment of Gulf War Veterans Illness
• VA HIV Vaccine Prepared-ness Study
• Effect of Methicillin Resistance among Staphylococcus aureus on the Expression of 4-Fluoroquinolone Resistance
• Individualized Dosing of Aminoglycosides
• Consequences of HTLV-III Infection for IV Drug Abusers
• Prospective Evaluation of teh Efficacy and Tolerance of Oral Trimethoprim-Sulfamethoxazole Prophylaxis in Neutropenic Patients
• Pathogenesis of Staphylococcal Endocarditis

Research Funding Sources

• Loyola University Medical Center
• National Institute of Drug Abuse
• VA Cooperative Studies
• VA Merit Review

Professional Accomplishments

• Member, American Society for Microbiology
• Fellow, American College of Physicians
• Member, American Federation for Medical Research
• Fellow, Infectious Diseases Society of America
• Member, Institute of Medicine - Chicago

Honors

• 1986 - Attending Physician of the Year, VA Housestaff Association