BIOGRAPHICAL SKETCH

Academic & Professional Background

• B.S. (Bioengineering) 1975 - Cornell University, Ithaca, New York
• M.S. (Neurobiology) 1977 - Purdue University, West Lafayette, Indiana
• Ph.D. (Biological Science) 1982 - Purdue University, West Lafayette, Indiana
• M.D. 1986 - Albert Einstein College of Medicine, Bronx, New York
• Transitional Intern 1987 - Jersey Shore Medical Center, Neptune, New Jersey
• Fellow in Ophthalmic Pathology 1988 - Armed Forces Institute of Pathology, Washington, DC
• Resident (Ophthalmology) 1991 - Bronx-Lebanon Hospital Center, Bronx, New York
• Fellow (Ophthalmic Pathology) 1993 - University of Illinois Eye and Ear Infirmary, Chicago

Current Research Interests

• Excitotoxicity
• Ophthalmic Pathology
• Retinal Ischemia
• Retinal Prostheses

Selected Publications

Pardue MT, Stubbs EB, Perlman JI, Narfstrom K, Chow AY, Peachey NS. Subretinal implantation of semiconductor-based photodiodes. Biocompatibility and function of novel implant designs and laser ablation of overlying retina. Exp Eye Res (in press), 2001.

Zimmerman R, Perlman JI. Bilateral acute post-operative retinal detachment after cataract extraction. A case report and review of the literature. J Cataract Refrac Surg (in press), 2001.

Valuck RJ, Perlman JI, Anderson C. Frequency of obstructive lung disease, congestive heart failure, and depression among users of topical beta blockers: Estimates from three U.S. veterans affairs medical centers. Pharmacoepidemiology and Drug Safety (in press), 2001.

VanderZanden JA, Valuck RJ, Bunch C, Perlman JI, Anderson C. Wortman GI. Systemic adverse effects of ophthalmic beta-blockers. Annals Pharmacotherapy (in press), 2001.

Bowen A, Perlman JI, Geiser R. Pathologic myopia with large peripapillary staphyloma. Retina (in press), 2001.

Chow AY, Pardue MT, Chow VY, Peyman GP, Liang C, Perlman JI, Peachey NS. Implantation of silicon chip microphotodiode arrays into the cat subretinal space. IEEE Transactions on Neural Systems and Rehabilitation Engineering 9:86-95, 2001.

Barba KR, Samy A, Perlman JI, Bouchard CS. Effect of topical anti-inflammatory drops on corneal and limbal wound healing. J Cataract Refrac Surg 26:893-897, 2000.

Skolnick KA, Perlman JI, Long DM, Kernan JM. Analysis and long-term follow-up of nd:yag posterior capsulotomies performed by ophthalmology residents at a Veterans Administration (VA) Hospital. J Cataract Refrac Surg 26:597-601, 2000.

Kleinman B, Perlman JI, Anderson C, Frey K, Stevens RA, Belusko R. A collaborative regional ocular anesthesia program: Successes and failures. J Clin Anesth 11:301-304, 1999.

Perlman JI, Shuber H, Selvaraj R, Cassidy EM. Free radical generation following pressure-induced retinal ischemia in the rat. Retina 19:255-257, 1999.

Li S, Perlman JI, Edward DP, Weiss R. Unilateral Blastomyces dermatitidis endophthalmitis and orbital cellulitis: A case report and literature review. Ophthalmology 105:1466-1470, 1998.

Peyman G, Chow AY, Liang C, Chow VY, Perlman JI, Peachey NS. Subretinal semiconductor microphotodiode array. Ophthalmic Surg Lasers 29:234-241, 1998.

Stubbs Jr. EB, Perlman JI, Peachey NS. Immunocytochemistry of NA,K-ATPase in the normal and tunicamycin-treated cat retina. Neurosci Lett 233:139-141, 1997.

Loeffler KU, Perlman JI. Diffuse intraepithelial sebaceous carcinoma of the conjunctiva. Brit J Ophthalmol 81:168, 1997.

Perlman JI, McCole SM, Pulluru P, Chang CJ, Lam TT, Tso MOM. Disturbances in the distribution of neurotransmitters in the rat retina after ischemia. Current Eye Research 15:589-596, 1996.

Perlman JI, Specht CS, McClean IW, Wolfe SA. Oncocytic adenocarcinoma of the lacrimal sac: Report of a case with paranasal sinus and orbital extension. Ophthalmic Surgery 26:377-379, 1995.

Perlman JI, Urban RC, Edward DP, Tso MOM. Syringocystadenoma papilliferum of the eyelid. Amer J Ophthalmol 117:647-650, 1994.

Korte GE, Perlman JI, Pollack A. Regeneration of mammalian retinal pigment epithelium. International Review of Cytology and Cell Biology 152:223-263, 1994.

Perlman JI, Forman S, Gonzalez ER. Retrobulbar ischemic optic neuropathy associated with sickle cell disease. J Neuro-Opthalmol 14:45-48, 1994.

Perlman JI, Piltz J, Korte G, Tzai C. Endocytosis in the rat retinal pigment epithelium. Acta Anat 135:354-360, 1989.

Perlman JI. Rhodopsin regeneration in the vertebrate retina. Einstein Quart J Biol Med 2:63-71, 1984.

Crouch R, Nodes BR, Perlman JI, Pepperberg DR, Akita H, Nakanishi K. Cycloheptatrienylidene analog of 11-cis retinal: Formation of pigment in photoreceptor membranes. Invest Ophthalmol Vis Sci 25:419-428, 1984.

Perlman JI, Nodes BR, Pepperberg DR. Utilization of retinoids in the bullfrog retina. J Gen Physiol 80:885-913, 1982.

Book Reviews

Eye Pathology: An Atlas and Basic Text, by Ralph C. Eagle, Jr., 1999. JAMA 283:122, 2000.

Effective Retinal Diagnosis, by Donald W. Novey and Kirk H. Packo, Video Parts 4A-4B, JAMA 282:1999.

Retina-Vitreous-Macula, edited by David R. Guyer, Lawrence A Uannuzzi, Stanley Chang, Jerry A Shields, and W. richard Green, vols 1-2, 1999. JAMA 282:695-696, 1999. (Co-reviewed with Dr. Mark Daily.)

Effective Retinal Diagnosis, by Donald W. Novey and Kirk H. Packo, Video Parts 1-3, JAMA 278:2196, 1997.

Ophthalmic Pathology: An Atlas and Textbook, edited by William H. Spencer, 1996. JAMA 276:1847, 1996.

Ocular Pathology, by Myron Yanoff and Ben S. Fine, 1996. JAMA 276:575, 1996.

Ophthalmic Pathology: A Color Atlas, by Myron Yanoff and Ben S. Fine, 1992. JAMA 269:2273, 1993.

Ophthalmology in Medicine: An Illustrated Clinical Guide, by David Abrams, 1990. Retina 12:180, 1992.

Intraocular Tumors: A Text and Atlas, by Jerry A. Shields and Carol L. Shields, 1992. JAMA 268:139, 1992.

Projects Completed or Active (Selected)

• Immunohistochemical Analysis of Excitotoxicity in Retinal Ischemia
• Pathology of the Photoreceptor Synapse
• Retinal Immunohistochemistry using a Vibratome
• Histopathology of Excitotoxicity and Free Radicals in Retinal Disease

Research Funding Sources

• Illinois Eye Fund
• Illinois Society for Prevention of Blindness
• National Institute of Health
• Prevent Blindness America
• VA Rehabilitation Research and Development
• VA Merit Review

Research Methods Employed

• Darkfield microscopy
• Immunohistochemistry

Professional Accomplishments

• 1987 - Diplomate, National Board of Medical Examiners
• 1992 - Diplomate, American Board of Ophthalmology

Honors

• 1992 - Heed Ophthalmic Fellowship
• 1992 - NIH National Research Service Award